Applications ↗
All Applications
Drug Discovery 13.2M/sec Cancer Therapeutics <17 min Oral Drug Delivery 80+ classes Gene Editing 24 targets Xenotransplantation 17/day saved Biodefense 13.2M/sec Brain-Computer Interface 80ns decode Genomics Pipeline 174× faster Precision Medicine 174× faster Protein Folding 370K atoms/30s Dental Imaging 53M px/sec Surgical Robotics 29× faster Hospital OS <100ms

22Rx

Treating you from first principles

Physics-first molecular simulation.
No neural networks. Pure force fields.

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The Engine

Not machine learning.
Navigation through chaos.

The Lattice of Navigable Chaos (LoNC) treats molecular interaction as a physics problem. No neural network. No training set. Every evaluation is derived from first principles — quantum mechanical force fields, electrostatic geometry, and fractal chaos navigation screening compound libraries against target proteins at speeds conventional methods can't match. Underneath it, the 44s lock-free compute architecture runs the simulation at speeds previously impossible on commodity hardware.

56B
Molecular configuration evaluations run to date
13.2M
Compound screens per second
15+
FDA-approved drug scaffolds matched in retrospective screening
0
Training examples required
LoNC — Lattice of Navigable Chaos
The screening layer
Fractal chaos navigation explores molecular configuration space the way water finds cracks in rock — following physics gradients, not lookup tables. Given any target protein, LoNC scores binding candidates from first principles — electrostatics, van der Waals forces, entropy — across massive compound libraries. The same engine that screens compounds also designs CRISPR guides, folds proteins, and evaluates pathogens for biodefense.
44s — Lock-Free Compute Architecture
The speed layer
Every existing compute system serializes concurrent operations with mutex locks. Under high load, threads wait. The 44s architecture eliminates locking entirely — atomic operations complete in under 1 microsecond, with linear scaling to any core count. The result: simulations that would take hours on conventional architecture complete in minutes. At 192 cores, throughput is 192× — not 10–20× like mutex-bound systems.
Retrospective Benchmarks

Screening known targets
against compound libraries.

We screened large compound libraries against known therapeutic targets using LoNC's physics-based scoring. The engine ranked known drug scaffolds among the top candidates — demonstrating throughput and scoring accuracy.

Paxlovid
COVID-19 — Mpro protease
FDA approved 2021 · Scaffold matched in 6 min screen
Remdesivir
COVID-19 — RdRp polymerase
FDA approved 2020 · Retrospective benchmark
Sotorasib
KRAS G12C lung cancer
FDA approved 2021 · Scaffold matched in 17 min screen
Donepezil
Alzheimer's — AChE inhibition
FDA approved 1996 · Retrospective benchmark
Memantine
Alzheimer's — NMDA modulation
FDA approved 2003 · Retrospective benchmark
Tofacitinib
Autoimmune — JAK1/JAK3
FDA approved 2012 · Pyrrolopyrimidine-class benchmark
Ruxolitinib
Autoimmune — JAK1/JAK2
FDA approved 2011 · Scaffold-class benchmark
Carbamazepine
Bipolar disorder — Nav channels
FDA approved 1974 · 180M compounds screened
Erlotinib
EGFR lung cancer
FDA approved 2004 · Quinazoline-class benchmark
Lenacapavir
HIV — capsid assembly
FDA approved 2022 · Mechanism-class benchmark

These results are retrospective screening benchmarks — known drug scaffolds were present in the compound libraries. The engine scored and ranked candidates using physics-based evaluation against known protein targets.

Applications

One engine.
Every biological problem.

The same physics-based simulation and lock-free compute architecture applies across every domain where biology meets computation.

13.2M/s
Drug Discovery
Physics-based small molecule screening. Any target. Any disease. No neural network required.
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<17 min
Cancer Therapeutics
KRAS scaffold screened in 17 minutes. Oral checkpoint inhibitors. Covalent warhead libraries for any oncotarget.
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80+
Oral Drug Delivery
Injectable drug classes converted to oral via GLP-1R ECD-mediated transcytosis. $350B market. Patent pending.
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24
Gene Editing
CRISPR, base editing, and prime editing guides designed with full-genome off-target validation in seconds.
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17/day
Xenotransplantation
Complete 5-layer pig-to-human compatibility edit suite. 106,000 on the transplant waitlist. Designed in under a minute.
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13.2M/s
Biodefense
H5N1, anthrax, plague, smallpox, Ebola. Complete countermeasure portfolios. Sequence-to-candidate in hours.
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80ns
Brain-Computer Interface
Sub-millisecond neural decoding. Closed-loop stimulation. Lock-free spike sorting at nanosecond latency.
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174×
Genomics Pipeline
Whole genome analysis in 8 minutes on commodity hardware. Faster than DRAGEN — no FPGA required.
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174×
Precision Medicine
Genomic-drug interaction screening at point of care. Adverse reaction prediction before the first dose.
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370K
Protein Folding
370,000 atom systems folded in 30 seconds. Lock-free parallel force field computation at any scale.
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53M/s
Dental Imaging
Fractal dimension analysis of dental radiographs. Cavities detected 6–18 months before visible. No AI, no cloud.
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29×
Surgical Robotics
0.34ms control loop vs da Vinci's 10ms. 2,938 Hz. Tremor sampled 2,600× per cycle. Telesurgery — now clinically viable.
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<100ms
Hospital OS
Lock-free EHR, real-time PACS imaging, millisecond sepsis alerts, unlimited concurrent chart access. Rebuilt from the OS up.
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